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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
17.88
Human Site:
S159
Identified Species:
32.78
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S159
A
T
P
E
F
L
R
S
I
Q
S
I
R
D
P
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S159
A
T
P
E
F
L
R
S
I
Q
S
I
R
D
P
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
S159
A
T
P
E
F
L
R
S
I
Q
S
I
R
D
P
Dog
Lupus familis
XP_537198
743
82483
S159
A
T
P
E
F
L
R
S
I
Q
S
V
R
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
N159
A
T
P
E
F
L
R
N
I
Q
S
V
R
D
P
Rat
Rattus norvegicus
Q5M9F8
807
89107
K176
N
G
G
G
P
P
N
K
G
I
P
E
L
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
K778
A
T
P
E
F
L
K
K
I
E
P
V
R
D
Q
Chicken
Gallus gallus
NP_001012613
698
77220
N158
E
N
L
L
T
A
L
N
D
Q
V
S
A
D
I
Frog
Xenopus laevis
Q561M0
827
91284
G174
E
N
T
A
P
R
K
G
V
E
M
E
K
Y
N
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
S159
A
T
P
E
F
L
K
S
I
Q
N
V
R
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
I145
L
N
I
N
T
Q
S
I
Y
V
T
E
S
G
S
Honey Bee
Apis mellifera
XP_001123124
613
70111
L76
L
Y
R
H
P
C
I
L
K
Y
V
S
S
W
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
N165
D
A
T
L
Q
F
L
N
Q
S
R
P
L
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
100
100
93.3
N.A.
86.6
0
N.A.
60
13.3
0
66.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
80
20
26.6
93.3
N.A.
6.6
0
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
8
0
8
0
8
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
0
0
0
0
54
0
% D
% Glu:
16
0
0
54
0
0
0
0
0
16
0
24
0
16
0
% E
% Phe:
0
0
0
0
54
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
8
0
0
0
8
8
0
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
8
54
8
0
24
0
0
8
% I
% Lys:
0
0
0
0
0
0
24
16
8
0
0
0
8
0
0
% K
% Leu:
16
0
8
16
0
54
16
8
0
0
0
0
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
24
0
8
0
0
8
24
0
0
8
0
0
0
24
% N
% Pro:
0
0
54
0
24
8
0
0
0
0
16
8
0
0
39
% P
% Gln:
0
0
0
0
8
8
0
0
8
54
0
0
0
0
16
% Q
% Arg:
0
0
8
0
0
8
39
0
0
0
8
0
54
8
0
% R
% Ser:
0
0
0
0
0
0
8
39
0
8
39
16
16
0
16
% S
% Thr:
0
54
16
0
16
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
8
16
31
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _